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Broad Institute Inc gene set enrichment analysis command line
(A) <t>GSEA</t> analysis showing Hallmark gene sets significantly differentially enriched (padj<0.05 and -1.5<Normalized enrichment score (NES) or NES>1.5) in WT-LPS vs WT (left) and/or in Tet2 -/- -LPS vs Tet2 -/- (right) comparisons. (B-E) Enrichment plots for E2F TARGETS (B-C) and TNF-α signalling via NF-κB (D-E) hallmark genesets in WT-LPS vs WT (B,D) and Tet2 -/- -LPS vs Tet2 -/- (C,E) conditions. NES: normalized enrichment score. (F-G) violin plot representing TE subfamilies expression for each TE subfamily significantly (p<0.05) differentially expressed in WT-LPS vs WT (F) and Tet2 -/- -LPS vs Tet2 -/- (G) conditions.
Gene Set Enrichment Analysis Command Line, supplied by Broad Institute Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/gene+set+enrichment+analysis+command+line/bio_rxiv__2025__07__21__665900-227-9-21?v=Broad+Institute+Inc
Average 90 stars, based on 1 article reviews
gene set enrichment analysis command line - by Bioz Stars, 2026-07
90/100 stars

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1) Product Images from "Differential sensitivity to LINE 1-induced damage contributes to the expansion of Tet2-deficient HSCs upon chronic inflammatory stress"

Article Title: Differential sensitivity to LINE 1-induced damage contributes to the expansion of Tet2-deficient HSCs upon chronic inflammatory stress

Journal: bioRxiv

doi: 10.1101/2025.07.21.665900

(A) GSEA analysis showing Hallmark gene sets significantly differentially enriched (padj<0.05 and -1.5<Normalized enrichment score (NES) or NES>1.5) in WT-LPS vs WT (left) and/or in Tet2 -/- -LPS vs Tet2 -/- (right) comparisons. (B-E) Enrichment plots for E2F TARGETS (B-C) and TNF-α signalling via NF-κB (D-E) hallmark genesets in WT-LPS vs WT (B,D) and Tet2 -/- -LPS vs Tet2 -/- (C,E) conditions. NES: normalized enrichment score. (F-G) violin plot representing TE subfamilies expression for each TE subfamily significantly (p<0.05) differentially expressed in WT-LPS vs WT (F) and Tet2 -/- -LPS vs Tet2 -/- (G) conditions.
Figure Legend Snippet: (A) GSEA analysis showing Hallmark gene sets significantly differentially enriched (padj<0.05 and -1.51.5) in WT-LPS vs WT (left) and/or in Tet2 -/- -LPS vs Tet2 -/- (right) comparisons. (B-E) Enrichment plots for E2F TARGETS (B-C) and TNF-α signalling via NF-κB (D-E) hallmark genesets in WT-LPS vs WT (B,D) and Tet2 -/- -LPS vs Tet2 -/- (C,E) conditions. NES: normalized enrichment score. (F-G) violin plot representing TE subfamilies expression for each TE subfamily significantly (p<0.05) differentially expressed in WT-LPS vs WT (F) and Tet2 -/- -LPS vs Tet2 -/- (G) conditions.

Techniques Used: Expressing



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Broad Institute Inc gene set enrichment analysis command line
(A) <t>GSEA</t> analysis showing Hallmark gene sets significantly differentially enriched (padj<0.05 and -1.5<Normalized enrichment score (NES) or NES>1.5) in WT-LPS vs WT (left) and/or in Tet2 -/- -LPS vs Tet2 -/- (right) comparisons. (B-E) Enrichment plots for E2F TARGETS (B-C) and TNF-α signalling via NF-κB (D-E) hallmark genesets in WT-LPS vs WT (B,D) and Tet2 -/- -LPS vs Tet2 -/- (C,E) conditions. NES: normalized enrichment score. (F-G) violin plot representing TE subfamilies expression for each TE subfamily significantly (p<0.05) differentially expressed in WT-LPS vs WT (F) and Tet2 -/- -LPS vs Tet2 -/- (G) conditions.
Gene Set Enrichment Analysis Command Line, supplied by Broad Institute Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/gene+set+enrichment+analysis+command+line/bio_rxiv__2025__07__21__665900-227-9-21?v=Broad+Institute+Inc
Average 90 stars, based on 1 article reviews
gene set enrichment analysis command line - by Bioz Stars, 2026-07
90/100 stars
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(A) GSEA analysis showing Hallmark gene sets significantly differentially enriched (padj<0.05 and -1.5<Normalized enrichment score (NES) or NES>1.5) in WT-LPS vs WT (left) and/or in Tet2 -/- -LPS vs Tet2 -/- (right) comparisons. (B-E) Enrichment plots for E2F TARGETS (B-C) and TNF-α signalling via NF-κB (D-E) hallmark genesets in WT-LPS vs WT (B,D) and Tet2 -/- -LPS vs Tet2 -/- (C,E) conditions. NES: normalized enrichment score. (F-G) violin plot representing TE subfamilies expression for each TE subfamily significantly (p<0.05) differentially expressed in WT-LPS vs WT (F) and Tet2 -/- -LPS vs Tet2 -/- (G) conditions.

Journal: bioRxiv

Article Title: Differential sensitivity to LINE 1-induced damage contributes to the expansion of Tet2-deficient HSCs upon chronic inflammatory stress

doi: 10.1101/2025.07.21.665900

Figure Lengend Snippet: (A) GSEA analysis showing Hallmark gene sets significantly differentially enriched (padj<0.05 and -1.51.5) in WT-LPS vs WT (left) and/or in Tet2 -/- -LPS vs Tet2 -/- (right) comparisons. (B-E) Enrichment plots for E2F TARGETS (B-C) and TNF-α signalling via NF-κB (D-E) hallmark genesets in WT-LPS vs WT (B,D) and Tet2 -/- -LPS vs Tet2 -/- (C,E) conditions. NES: normalized enrichment score. (F-G) violin plot representing TE subfamilies expression for each TE subfamily significantly (p<0.05) differentially expressed in WT-LPS vs WT (F) and Tet2 -/- -LPS vs Tet2 -/- (G) conditions.

Article Snippet: For pathway enrichment analysis and data visualization, we performed Gene Set Enrichment Analysis (GSEA) using the GSEA command line (v 4.3.3, Broad Institute) ( ).

Techniques: Expressing